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Phenotypic Mutation Rates and the Abundance of Abnormal Proteins in Yeast

Phenotypic mutations are errors that occur during protein synthesis. These errors lead to amino acid substitutions that give rise to abnormal proteins. Experiments suggest that such errors are quite common. We present a model to study the effect of phenotypic mutation rates on the amount of abnormal...

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Detalles Bibliográficos
Autores principales: Willensdorfer, Martin, Bürger, Reinhard, Nowak, Martin A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082502/
https://www.ncbi.nlm.nih.gov/pubmed/18039025
http://dx.doi.org/10.1371/journal.pcbi.0030203

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