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Primary presacral neuroendocrine tumor associated with imperforate anus
BACKGROUND: Presacral masses are unusual growths that have a limited differential diagnosis, typically not including neuroendocrine tumors (NETs). Classically, NETs are well-differentiated gastroenteropancreatic tumors of probable benign behavior. These tumors are associated with a typical morpholog...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2092435/ https://www.ncbi.nlm.nih.gov/pubmed/17931412 http://dx.doi.org/10.1186/1477-7819-5-115 |
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author | Kim, Tad Grobmyer, Stephen R Liu, Chen Hochwald, Steven N |
author_facet | Kim, Tad Grobmyer, Stephen R Liu, Chen Hochwald, Steven N |
author_sort | Kim, Tad |
collection | PubMed |
description | BACKGROUND: Presacral masses are unusual growths that have a limited differential diagnosis, typically not including neuroendocrine tumors (NETs). Classically, NETs are well-differentiated gastroenteropancreatic tumors of probable benign behavior. These tumors are associated with a typical morphologic pattern and involve the distal colon, rectum, and genitourinary tract; they are considered less aggressive, frequently asymptomatic, and rarely cause carcinoid syndrome, even when metastatic. Neuroendocrine tumors of the presacral region are extremely rare and few have been described in the literature. They have not been previously reported as being associated with imperforate anus. CASE PRESENTATION: We present an interesting case of a woman with a history of imperforate anus that was found to have a primary neuroendocrine tumor of the presacral region with no rectal wall involvement. CONCLUSION: We argue that this is a primary gastroenteropancreatic neuroendocrine tumor which likely originated from cells of hindgut origin that underwent an abnormal migration during embryonic development. |
format | Text |
id | pubmed-2092435 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-20924352007-11-23 Primary presacral neuroendocrine tumor associated with imperforate anus Kim, Tad Grobmyer, Stephen R Liu, Chen Hochwald, Steven N World J Surg Oncol Case Report BACKGROUND: Presacral masses are unusual growths that have a limited differential diagnosis, typically not including neuroendocrine tumors (NETs). Classically, NETs are well-differentiated gastroenteropancreatic tumors of probable benign behavior. These tumors are associated with a typical morphologic pattern and involve the distal colon, rectum, and genitourinary tract; they are considered less aggressive, frequently asymptomatic, and rarely cause carcinoid syndrome, even when metastatic. Neuroendocrine tumors of the presacral region are extremely rare and few have been described in the literature. They have not been previously reported as being associated with imperforate anus. CASE PRESENTATION: We present an interesting case of a woman with a history of imperforate anus that was found to have a primary neuroendocrine tumor of the presacral region with no rectal wall involvement. CONCLUSION: We argue that this is a primary gastroenteropancreatic neuroendocrine tumor which likely originated from cells of hindgut origin that underwent an abnormal migration during embryonic development. BioMed Central 2007-10-11 /pmc/articles/PMC2092435/ /pubmed/17931412 http://dx.doi.org/10.1186/1477-7819-5-115 Text en Copyright © 2007 Kim et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Tad Grobmyer, Stephen R Liu, Chen Hochwald, Steven N Primary presacral neuroendocrine tumor associated with imperforate anus |
title | Primary presacral neuroendocrine tumor associated with imperforate anus |
title_full | Primary presacral neuroendocrine tumor associated with imperforate anus |
title_fullStr | Primary presacral neuroendocrine tumor associated with imperforate anus |
title_full_unstemmed | Primary presacral neuroendocrine tumor associated with imperforate anus |
title_short | Primary presacral neuroendocrine tumor associated with imperforate anus |
title_sort | primary presacral neuroendocrine tumor associated with imperforate anus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2092435/ https://www.ncbi.nlm.nih.gov/pubmed/17931412 http://dx.doi.org/10.1186/1477-7819-5-115 |
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