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Functional analysis of human mutations in homeodomain transcription factor PITX3

BACKGROUND: The homeodomain-containing transcription factor PITX3 was shown to be essential for normal eye development in vertebrates. Human patients with point mutations in PITX3 demonstrate congenital cataracts along with anterior segment defects in some cases when one allele is affected and micro...

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Detalles Bibliográficos
Autores principales:	Sakazume, Satoru, Sorokina, Elena, Iwamoto, Yoshiki, Semina, Elena V
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093940/ https://www.ncbi.nlm.nih.gov/pubmed/17888164 http://dx.doi.org/10.1186/1471-2199-8-84

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