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Stabilization of SMAR1 mRNA by PGA2 involves a stem–loop structure in the 5′ UTR
Prostaglandins are anticancer agents known to inhibit tumor cell proliferation both in vitro and in vivo by affecting the mRNA stability. Here we report that a MAR-binding protein SMAR1 is a target of Prostaglandin A2 (PGA2) induced growth arrest. We identify a regulatory mechanism leading to stabil...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094063/ https://www.ncbi.nlm.nih.gov/pubmed/17726044 http://dx.doi.org/10.1093/nar/gkm649 |