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Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation

Translation of most eukaryotic mRNAs involves the synergistic action between the 5′ cap structure and the 3′ poly(A) tail at the initiation step. The poly(A) tail has also been shown to stimulate translation of picornavirus internal ribosome entry sites (IRES)-directed translation. These effects hav...

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Detalles Bibliográficos
Autores principales: Rifo, Ricardo Soto, Ricci, Emiliano P., Décimo, Didier, Moncorgé, Olivier, Ohlmann, Théophile
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094066/
https://www.ncbi.nlm.nih.gov/pubmed/17881372
http://dx.doi.org/10.1093/nar/gkm682