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Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination

Targeted chromatin remodelling is essential for many nuclear processes, including the regulation of V(D)J recombination. ATP-dependent nucleosome remodelling complexes are important players in this process whose activity must be tightly regulated. We show here that histone acetylation regulates nucl...

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Detalles Bibliográficos
Autores principales: Nightingale, Karl P., Baumann, Matthias, Eberharter, Anton, Mamais, Adamantios, Becker, Peter B., Boyes, Joan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094086/
https://www.ncbi.nlm.nih.gov/pubmed/17881376
http://dx.doi.org/10.1093/nar/gkm650