High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes

The global transcriptional regulator H-NS selectively silences bacterial genes associated with pathogenicity and responses to environmental insults. Although there is ample evidence that H-NS binds preferentially to DNA containing curved regions, we show here that a major basis for this selectivity...

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Detalles Bibliográficos
Autores principales: Lang, Benjamin, Blot, Nicolas, Bouffartigues, Emeline, Buckle, Malcolm, Geertz, Marcel, Gualerzi, Claudio O., Mavathur, Ramesh, Muskhelishvili, Georgi, Pon, Cynthia L., Rimsky, Sylvie, Stella, Stefano, Babu, M. Madan, Travers, Andrew
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094087/
https://www.ncbi.nlm.nih.gov/pubmed/17881364
http://dx.doi.org/10.1093/nar/gkm712

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