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Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements

CpG methylation is a key component of the epigenome architecture that is associated with changes in gene expression without a change to the DNA sequence. Since the first reports on deregulation of DNA methylation, in diseases such as cancer, and the initiation of the Human Epigenome Project, an incr...

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Detalles Bibliográficos
Autores principales: Coolen, Marcel W., Statham, Aaron L., Gardiner-Garden, Margaret, Clark, Susan J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094090/
https://www.ncbi.nlm.nih.gov/pubmed/17855397
http://dx.doi.org/10.1093/nar/gkm662

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