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Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging
BACKGROUND: Long-lived strains of dwarf mice carry mutations that suppress growth hormone (GH) and insulin-like growth factor I (IGF-I) signaling. The downstream effects of these endocrine abnormalities, however, are not well understood and it is unclear how these processes interact with aging mecha...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094713/ https://www.ncbi.nlm.nih.gov/pubmed/17915019 http://dx.doi.org/10.1186/1471-2164-8-353 |