Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

Administration of small interfering RNAs (siRNAs) leads to degradation of specific mRNAs utilizing the cellular RNA interference (RNAi) machinery. It has been demonstrated that co-administration of siRNAs may lead to attenuation of activity of one of the siRNAs. Utilizing antisense and siRNA-mediate...

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Detalles Bibliográficos
Autores principales: Vickers, Timothy A., Lima, Walt F., Nichols, Josh G., Crooke, Stanley T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095815/
https://www.ncbi.nlm.nih.gov/pubmed/17905815
http://dx.doi.org/10.1093/nar/gkm663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095815/
https://www.ncbi.nlm.nih.gov/pubmed/17905815
http://dx.doi.org/10.1093/nar/gkm663

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