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Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells
Administration of small interfering RNAs (siRNAs) leads to degradation of specific mRNAs utilizing the cellular RNA interference (RNAi) machinery. It has been demonstrated that co-administration of siRNAs may lead to attenuation of activity of one of the siRNAs. Utilizing antisense and siRNA-mediate...
Autores principales: | Vickers, Timothy A., Lima, Walt F., Nichols, Josh G., Crooke, Stanley T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095815/ https://www.ncbi.nlm.nih.gov/pubmed/17905815 http://dx.doi.org/10.1093/nar/gkm663 |
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