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FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations

Real-time signal generation methods for detection and characterization of low-abundance mutations in genomic DNA are powerful tools for cancer diagnosis and prognosis. Mutations in codon 12 of the oncogene KRAS, for example, are frequently found in several types of human cancers. We have developed a...

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Detalles Bibliográficos
Autores principales: Amicarelli, Giulia, Shehi, Erlet, Makrigiorgos, G. Mike, Adlerstein, Daniel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095824/
https://www.ncbi.nlm.nih.gov/pubmed/17932053
http://dx.doi.org/10.1093/nar/gkm809