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2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors
The synthesis of a series of 9-ethyladenine derivatives bearing alkynyl chains in 2- or 8-position was undertaken, based on the observation that replacement of the sugar moiety in adenosine derivatives with alkyl groups led to adenosine receptor antagonists. All the synthesized compounds were tested...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096531/ https://www.ncbi.nlm.nih.gov/pubmed/18404502 http://dx.doi.org/10.1007/s11302-005-6216-y |