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Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4(+)CD25(- )T cells

BACKGROUND: CD4(+)CD25(+ )T regulatory cells (Tregs) play an important role in regulating immune responses, and in influencing human immune diseases such as HIV infection. It has been shown that human CD4(+)CD25(+ )Tregs can be induced in vitro by TCR stimulation of CD4(+)CD25(- )T cells. However, t...

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Detalles Bibliográficos
Autores principales:	Amarnath, Shoba, Dong, Li, Li, Jun, Wu, Yuntao, Chen, WanJun
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096626/ https://www.ncbi.nlm.nih.gov/pubmed/17688698 http://dx.doi.org/10.1186/1742-4690-4-57

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