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Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A(3) adenosine receptor ligands

A series of 2-phenylethynyladenosine (PEAdo) derivatives substituted in the N(6)- and 4′position was synthesised and the new derivatives were tested at the four human adenosine receptors stably transfected into Chinese hamster ovary (CHO) cells, using radioligand binding studies (A(1), A(2A), A(3))...

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Detalles Bibliográficos
Autores principales: Dal Ben, Diego, Lambertucci, Catia, Taffi, Sara, Vittori, Sauro, Volpini, Rosaria, Cristalli, Gloria, Klotz, Karl-Norbert
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096654/
https://www.ncbi.nlm.nih.gov/pubmed/18404461
http://dx.doi.org/10.1007/s11302-006-9010-6