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In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators

Early identification of adverse effect of preclinical and commercial drugs is crucial in developing highly efficient therapeutics, since unexpected adverse drug effects account for one-third of all drug failures in drug development. To correlate protein–drug interactions at the molecule level with t...

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Detalles Bibliográficos
Autores principales: Xie, Lei, Wang, Jian, Bourne, Philip E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098847/
https://www.ncbi.nlm.nih.gov/pubmed/18052534
http://dx.doi.org/10.1371/journal.pcbi.0030217

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