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In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators
Early identification of adverse effect of preclinical and commercial drugs is crucial in developing highly efficient therapeutics, since unexpected adverse drug effects account for one-third of all drug failures in drug development. To correlate protein–drug interactions at the molecule level with t...
Autores principales: | Xie, Lei, Wang, Jian, Bourne, Philip E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098847/ https://www.ncbi.nlm.nih.gov/pubmed/18052534 http://dx.doi.org/10.1371/journal.pcbi.0030217 |
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