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CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures

We present CATHEDRAL, an iterative protocol for determining the location of previously observed protein folds in novel multidomain protein structures. CATHEDRAL builds on the features of a fast secondary-structure–based method (using graph theory) to locate known folds within a multidomain context a...

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Detalles Bibliográficos
Autores principales: Redfern, Oliver C, Harrison, Andrew, Dallman, Tim, Pearl, Frances M. G, Orengo, Christine A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098860/
https://www.ncbi.nlm.nih.gov/pubmed/18052539
http://dx.doi.org/10.1371/journal.pcbi.0030232