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Predicting Protein Function with Hierarchical Phylogenetic Profiles: The Gene3D Phylo-Tuner Method Applied to Eukaryotic Genomes

“Phylogenetic profiling” is based on the hypothesis that during evolution functionally or physically interacting genes are likely to be inherited or eliminated in a codependent manner. Creating presence–absence profiles of orthologous genes is now a common and powerful way of identifying functionall...

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Detalles Bibliográficos
Autores principales: Ranea, Juan A. G, Yeats, Corin, Grant, Alastair, Orengo, Christine A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098864/
https://www.ncbi.nlm.nih.gov/pubmed/18052542
http://dx.doi.org/10.1371/journal.pcbi.0030237