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Direct Inference of SNP Heterozygosity Rates and Resolution of LOH Detection

Single nucleotide polymorphisms (SNPs) have been increasingly utilized to investigate somatic genetic abnormalities in premalignancy and cancer. LOH is a common alteration observed during cancer development, and SNP assays have been used to identify LOH at specific chromosomal regions. The design of...

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Detalles Bibliográficos
Autores principales:	Li, Xiaohong, Self, Steven G, Galipeau, Patricia C, Paulson, Thomas G, Reid, Brian J
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2098867/ https://www.ncbi.nlm.nih.gov/pubmed/18052545 http://dx.doi.org/10.1371/journal.pcbi.0030244

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