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Kinetic Mechanism of the Ca(2+)-Dependent Switch-On and Switch-Off of Cardiac Troponin in Myofibrils

The kinetics of Ca(2+)-dependent conformational changes of human cardiac troponin (cTn) were studied on isolated cTn and within the sarcomeric environment of myofibrils. Human cTnC was selectively labeled on cysteine 84 with N-((2-(iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole and...

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Detalles Bibliográficos
Autores principales:	Solzin, Johannes, Iorga, Bogdan, Sierakowski, Eva, Gomez Alcazar, Diana P., Ruess, Daniel F., Kubacki, Torsten, Zittrich, Stefan, Blaudeck, Natascha, Pfitzer, Gabriele, Stehle, Robert
Formato:	Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2007
Materias:	Muscle and Contractility
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099212/ https://www.ncbi.nlm.nih.gov/pubmed/17704185 http://dx.doi.org/10.1529/biophysj.107.111146

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