Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription factor binding, retroviral DNA terminus dynamics, and retroviral integrase-DNA binding

BACKGROUND: Synthetic transcription factors (STFs) promise to offer a powerful new therapeutic against Cancer, AIDS, and genetic disease. Currently, 10% of drugs are of this type, including salicylate and tamoxifen. STFs that can appropriately target (and release) their transcription factor binding...

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Detalles Bibliográficos
Autores principales: Winters-Hilt, Stephen, Davis, Amanda, Amin, Iftekhar, Morales, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099478/
https://www.ncbi.nlm.nih.gov/pubmed/18047709
http://dx.doi.org/10.1186/1471-2105-8-S7-S10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099478/
https://www.ncbi.nlm.nih.gov/pubmed/18047709
http://dx.doi.org/10.1186/1471-2105-8-S7-S10

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