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Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
BACKGROUND: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel in the pA-nA range. A distinctive channel current blockade signal is created as individually "captured" DNA mol...
Autores principales: | Landry, Matthew, Winters-Hilt, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099480/ https://www.ncbi.nlm.nih.gov/pubmed/18047711 http://dx.doi.org/10.1186/1471-2105-8-S7-S12 |
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