THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS

Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene solution followed by repeated applications of croton oil solutions. Fourteen benign and malignant tumors were sampled 25 weeks after the treatment had begun, fixed in osmium tetroxide or p...

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Detalles Bibliográficos
Autor principal: Frei, J. V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1962
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106146/
https://www.ncbi.nlm.nih.gov/pubmed/13959516
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author Frei, J. V.
author_facet Frei, J. V.
author_sort Frei, J. V.
collection PubMed
description Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene solution followed by repeated applications of croton oil solutions. Fourteen benign and malignant tumors were sampled 25 weeks after the treatment had begun, fixed in osmium tetroxide or potassium permanganate, and embedded in Epon. Sections stained with lead hydroxide were examined. In three tumors defects of the epidermal basement membrane were seen. These defects accompanied local invasion of the tumors. The possible mechanisms of the development of this unusual anatomical situation are discussed.
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spelling pubmed-21061462008-05-01 THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS Frei, J. V. J Cell Biol Article Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene solution followed by repeated applications of croton oil solutions. Fourteen benign and malignant tumors were sampled 25 weeks after the treatment had begun, fixed in osmium tetroxide or potassium permanganate, and embedded in Epon. Sections stained with lead hydroxide were examined. In three tumors defects of the epidermal basement membrane were seen. These defects accompanied local invasion of the tumors. The possible mechanisms of the development of this unusual anatomical situation are discussed. The Rockefeller University Press 1962-11-01 /pmc/articles/PMC2106146/ /pubmed/13959516 Text en Copyright © Copyright, 1962, by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Frei, J. V.
THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title_full THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title_fullStr THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title_full_unstemmed THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title_short THE FINE STRUCTURE OF THE BASEMENT MEMBRANE IN EPIDERMAL TUMORS
title_sort fine structure of the basement membrane in epidermal tumors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106146/
https://www.ncbi.nlm.nih.gov/pubmed/13959516
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AT freijv finestructureofthebasementmembraneinepidermaltumors

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