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INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION
Several parameters of meiosis have been studied in cultured anthers of Trillium erectum. The accessibility of labeled substrates to meiotic cells and the fate of these substrates in relation to meiotic stage have been determined. Evidence has been adduced for the synthesis of RNA and protein during...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1963
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106253/ https://www.ncbi.nlm.nih.gov/pubmed/13955016 |
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author | Hotta, Yasuo Stern, Herbert |
author_facet | Hotta, Yasuo Stern, Herbert |
author_sort | Hotta, Yasuo |
collection | PubMed |
description | Several parameters of meiosis have been studied in cultured anthers of Trillium erectum. The accessibility of labeled substrates to meiotic cells and the fate of these substrates in relation to meiotic stage have been determined. Evidence has been adduced for the synthesis of RNA and protein during the meiotic cycle well after chromosome duplication. The effect of interfering with systems directly or indirectly connected with protein formation has been studied by means of chloramphenicol, 8-azaguanine, 5-methyltryptophan, and ethionine. Administration of these reagents at different intervals in the cycle elicits correspondingly different responses thereby indicating a periodicity in the activities of different systems. The following processes have been shown to be affected in these experiments: chromosome segregation, chromosome morphology, cytokinesis, wall synthesis, and enzyme appearance. The possibility of experimentally altering the normal sequence of events has also been shown. |
format | Text |
id | pubmed-2106253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1963 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21062532008-05-01 INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION Hotta, Yasuo Stern, Herbert J Cell Biol Article Several parameters of meiosis have been studied in cultured anthers of Trillium erectum. The accessibility of labeled substrates to meiotic cells and the fate of these substrates in relation to meiotic stage have been determined. Evidence has been adduced for the synthesis of RNA and protein during the meiotic cycle well after chromosome duplication. The effect of interfering with systems directly or indirectly connected with protein formation has been studied by means of chloramphenicol, 8-azaguanine, 5-methyltryptophan, and ethionine. Administration of these reagents at different intervals in the cycle elicits correspondingly different responses thereby indicating a periodicity in the activities of different systems. The following processes have been shown to be affected in these experiments: chromosome segregation, chromosome morphology, cytokinesis, wall synthesis, and enzyme appearance. The possibility of experimentally altering the normal sequence of events has also been shown. The Rockefeller University Press 1963-02-01 /pmc/articles/PMC2106253/ /pubmed/13955016 Text en Copyright © Copyright, 1963, by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Hotta, Yasuo Stern, Herbert INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title | INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title_full | INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title_fullStr | INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title_full_unstemmed | INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title_short | INHIBITION OF PROTEIN SYNTHESES DURING MEIOSIS AND ITS BEARING ON INTRACELLULAR REGULATION |
title_sort | inhibition of protein syntheses during meiosis and its bearing on intracellular regulation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106253/ https://www.ncbi.nlm.nih.gov/pubmed/13955016 |
work_keys_str_mv | AT hottayasuo inhibitionofproteinsynthesesduringmeiosisanditsbearingonintracellularregulation AT sternherbert inhibitionofproteinsynthesesduringmeiosisanditsbearingonintracellularregulation |