THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION

Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative...

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Detalles Bibliográficos
Autores principales: Tonna, Edgar A., Cronkite, Eugene P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1964
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106514/
https://www.ncbi.nlm.nih.gov/pubmed/14228520
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author Tonna, Edgar A.
Cronkite, Eugene P.
author_facet Tonna, Edgar A.
Cronkite, Eugene P.
author_sort Tonna, Edgar A.
collection PubMed
description Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative response of the cells in the periosteum was similar. These studies have shown that neither bone fracture nor direct disruption of the periosteum is necessary to induce periosteal cell proliferation since a single extraperiosteal injection of physiological saline induces DNA synthesis.
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spelling pubmed-21065142008-05-01 THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION Tonna, Edgar A. Cronkite, Eugene P. J Cell Biol Article Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative response of the cells in the periosteum was similar. These studies have shown that neither bone fracture nor direct disruption of the periosteum is necessary to induce periosteal cell proliferation since a single extraperiosteal injection of physiological saline induces DNA synthesis. The Rockefeller University Press 1964-10-01 /pmc/articles/PMC2106514/ /pubmed/14228520 Text en Copyright © 1964 by The Rockefeller Institute Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Tonna, Edgar A.
Cronkite, Eugene P.
THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title_full THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title_fullStr THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title_full_unstemmed THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title_short THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
title_sort effects of extraperiosteal injections of blood components on periosteal cell proliferation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106514/
https://www.ncbi.nlm.nih.gov/pubmed/14228520
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