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RENEWAL OF CELLS WITHIN TASTE BUDS

Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using triti...

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Detalles Bibliográficos
Autores principales: Beidler, Lloyd M., Smallman, Ronald L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106718/
https://www.ncbi.nlm.nih.gov/pubmed/5884625
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author Beidler, Lloyd M.
Smallman, Ronald L.
author_facet Beidler, Lloyd M.
Smallman, Ronald L.
author_sort Beidler, Lloyd M.
collection PubMed
description Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using tritiated thymidine, shows that those epithelial cells surrounding the taste bud divide and that some of the daughter cells enter the taste bud and slowly move toward the center. The life span of the average cell is about 250 ± 50 hours, although some cells have a much shorter and others a much longer life span. These studies suggest that the cells within the taste bud, as well as the nerves, undergo considerable change with time. Corresponding changes in function are considered.
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spelling pubmed-21067182008-05-01 RENEWAL OF CELLS WITHIN TASTE BUDS Beidler, Lloyd M. Smallman, Ronald L. J Cell Biol Article Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using tritiated thymidine, shows that those epithelial cells surrounding the taste bud divide and that some of the daughter cells enter the taste bud and slowly move toward the center. The life span of the average cell is about 250 ± 50 hours, although some cells have a much shorter and others a much longer life span. These studies suggest that the cells within the taste bud, as well as the nerves, undergo considerable change with time. Corresponding changes in function are considered. The Rockefeller University Press 1965-11-01 /pmc/articles/PMC2106718/ /pubmed/5884625 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Beidler, Lloyd M.
Smallman, Ronald L.
RENEWAL OF CELLS WITHIN TASTE BUDS
title RENEWAL OF CELLS WITHIN TASTE BUDS
title_full RENEWAL OF CELLS WITHIN TASTE BUDS
title_fullStr RENEWAL OF CELLS WITHIN TASTE BUDS
title_full_unstemmed RENEWAL OF CELLS WITHIN TASTE BUDS
title_short RENEWAL OF CELLS WITHIN TASTE BUDS
title_sort renewal of cells within taste buds
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106718/
https://www.ncbi.nlm.nih.gov/pubmed/5884625
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