Cargando…
RENEWAL OF CELLS WITHIN TASTE BUDS
Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using triti...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1965
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106718/ https://www.ncbi.nlm.nih.gov/pubmed/5884625 |
_version_ | 1782138576814735360 |
---|---|
author | Beidler, Lloyd M. Smallman, Ronald L. |
author_facet | Beidler, Lloyd M. Smallman, Ronald L. |
author_sort | Beidler, Lloyd M. |
collection | PubMed |
description | Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using tritiated thymidine, shows that those epithelial cells surrounding the taste bud divide and that some of the daughter cells enter the taste bud and slowly move toward the center. The life span of the average cell is about 250 ± 50 hours, although some cells have a much shorter and others a much longer life span. These studies suggest that the cells within the taste bud, as well as the nerves, undergo considerable change with time. Corresponding changes in function are considered. |
format | Text |
id | pubmed-2106718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1965 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21067182008-05-01 RENEWAL OF CELLS WITHIN TASTE BUDS Beidler, Lloyd M. Smallman, Ronald L. J Cell Biol Article Colchicine blocks mitotic division of the epithelial cells surrounding the taste bud of the rat tongue. Response to chemical stimulation decreases 50 per cent 3 hours after colchicine injection as measured by recording the electrical activity from the taste nerve bundle. Radioautography, using tritiated thymidine, shows that those epithelial cells surrounding the taste bud divide and that some of the daughter cells enter the taste bud and slowly move toward the center. The life span of the average cell is about 250 ± 50 hours, although some cells have a much shorter and others a much longer life span. These studies suggest that the cells within the taste bud, as well as the nerves, undergo considerable change with time. Corresponding changes in function are considered. The Rockefeller University Press 1965-11-01 /pmc/articles/PMC2106718/ /pubmed/5884625 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Beidler, Lloyd M. Smallman, Ronald L. RENEWAL OF CELLS WITHIN TASTE BUDS |
title | RENEWAL OF CELLS WITHIN TASTE BUDS |
title_full | RENEWAL OF CELLS WITHIN TASTE BUDS |
title_fullStr | RENEWAL OF CELLS WITHIN TASTE BUDS |
title_full_unstemmed | RENEWAL OF CELLS WITHIN TASTE BUDS |
title_short | RENEWAL OF CELLS WITHIN TASTE BUDS |
title_sort | renewal of cells within taste buds |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106718/ https://www.ncbi.nlm.nih.gov/pubmed/5884625 |
work_keys_str_mv | AT beidlerlloydm renewalofcellswithintastebuds AT smallmanronaldl renewalofcellswithintastebuds |