REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report

Within 3.5 to 4 hours after thionine administration, numerous small osmiophilic bodies, liposomes, appear in the endoplasmic reticulum of the liver cells. By fusion, the liposomes lead to the formation of larger collections of fat, giant liposomes. Adenine administration to ethionine-treated rats re...

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Detalles Bibliográficos
Autores principales: Baglio, Corrado M., Farber, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106760/
https://www.ncbi.nlm.nih.gov/pubmed/5885431
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author Baglio, Corrado M.
Farber, Emmanuel
author_facet Baglio, Corrado M.
Farber, Emmanuel
author_sort Baglio, Corrado M.
collection PubMed
description Within 3.5 to 4 hours after thionine administration, numerous small osmiophilic bodies, liposomes, appear in the endoplasmic reticulum of the liver cells. By fusion, the liposomes lead to the formation of larger collections of fat, giant liposomes. Adenine administration to ethionine-treated rats removes the liposomes from the hepatocytes and causes the transitory appearance of osmiophilic droplets in the sinusoidal space of Disse. The characteristic disaggregation of hepatic polysomes seen in the liver after ethionine administration is corrected by the injection of adenine.
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spelling pubmed-21067602008-05-01 REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report Baglio, Corrado M. Farber, Emmanuel J Cell Biol Article Within 3.5 to 4 hours after thionine administration, numerous small osmiophilic bodies, liposomes, appear in the endoplasmic reticulum of the liver cells. By fusion, the liposomes lead to the formation of larger collections of fat, giant liposomes. Adenine administration to ethionine-treated rats removes the liposomes from the hepatocytes and causes the transitory appearance of osmiophilic droplets in the sinusoidal space of Disse. The characteristic disaggregation of hepatic polysomes seen in the liver after ethionine administration is corrected by the injection of adenine. The Rockefeller University Press 1965-12-01 /pmc/articles/PMC2106760/ /pubmed/5885431 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Baglio, Corrado M.
Farber, Emmanuel
REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title_full REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title_fullStr REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title_full_unstemmed REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title_short REVERSAL BY ADENINE OF THE ETHIONINE-INDUCED LIPID ACCUMULATION IN THE ENDOPLASMIC RETICULUM OF THE RAT LIVER : A Preliminary Report
title_sort reversal by adenine of the ethionine-induced lipid accumulation in the endoplasmic reticulum of the rat liver : a preliminary report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106760/
https://www.ncbi.nlm.nih.gov/pubmed/5885431
work_keys_str_mv AT bagliocorradom reversalbyadenineoftheethionineinducedlipidaccumulationintheendoplasmicreticulumoftheratliverapreliminaryreport
AT farberemmanuel reversalbyadenineoftheethionineinducedlipidaccumulationintheendoplasmicreticulumoftheratliverapreliminaryreport

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