A SPECIAL FIBRIL OF THE DERMIS

A new type of extracellular fibril is described in the dermis of Bufo marinus, Rana pipiens, and Amblystoma punctatum. It is restricted in distribution to the dermal micropapillae and the region immediately below them in the stratum spongiosum. The fibrils (diameter = 200 to 750 A) are lateral aggre...

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Detalles Bibliográficos
Autores principales: Palade, George E., Farquhar, Marilyn G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1965
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106801/
https://www.ncbi.nlm.nih.gov/pubmed/5857257
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author Palade, George E.
Farquhar, Marilyn G.
author_facet Palade, George E.
Farquhar, Marilyn G.
author_sort Palade, George E.
collection PubMed
description A new type of extracellular fibril is described in the dermis of Bufo marinus, Rana pipiens, and Amblystoma punctatum. It is restricted in distribution to the dermal micropapillae and the region immediately below them in the stratum spongiosum. The fibrils (diameter = 200 to 750 A) are lateral aggregates of fine filaments and have a unique banding pattern characterized by absence of recognizable periodicity and by polarization in respect to the basement membrane. Their distal(1) ends are anchored in the basement membrane, and their proximal ends converge in knots located in the middle region of the micropapillae. These anchoring fibrils seem to secure the minute outfoldings of the basement membrane along the dermal-epidermal junction. Comparable, but less frequent, fibrils are also encountered along the proximal aspect of the basement membrane in the skin, lingual mucosa, and mucosa of the gastric fundus in the rat.
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spelling pubmed-21068012008-05-01 A SPECIAL FIBRIL OF THE DERMIS Palade, George E. Farquhar, Marilyn G. J Cell Biol Article A new type of extracellular fibril is described in the dermis of Bufo marinus, Rana pipiens, and Amblystoma punctatum. It is restricted in distribution to the dermal micropapillae and the region immediately below them in the stratum spongiosum. The fibrils (diameter = 200 to 750 A) are lateral aggregates of fine filaments and have a unique banding pattern characterized by absence of recognizable periodicity and by polarization in respect to the basement membrane. Their distal(1) ends are anchored in the basement membrane, and their proximal ends converge in knots located in the middle region of the micropapillae. These anchoring fibrils seem to secure the minute outfoldings of the basement membrane along the dermal-epidermal junction. Comparable, but less frequent, fibrils are also encountered along the proximal aspect of the basement membrane in the skin, lingual mucosa, and mucosa of the gastric fundus in the rat. The Rockefeller University Press 1965-10-01 /pmc/articles/PMC2106801/ /pubmed/5857257 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Palade, George E.
Farquhar, Marilyn G.
A SPECIAL FIBRIL OF THE DERMIS
title A SPECIAL FIBRIL OF THE DERMIS
title_full A SPECIAL FIBRIL OF THE DERMIS
title_fullStr A SPECIAL FIBRIL OF THE DERMIS
title_full_unstemmed A SPECIAL FIBRIL OF THE DERMIS
title_short A SPECIAL FIBRIL OF THE DERMIS
title_sort special fibril of the dermis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106801/
https://www.ncbi.nlm.nih.gov/pubmed/5857257
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AT farquharmarilyng aspecialfibrilofthedermis
AT paladegeorgee specialfibrilofthedermis
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