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Transposons as tools for enhancer trap screens in vertebrates

DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the...

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Detalles Bibliográficos
Autor principal: Korzh, Vladimir
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106835/
https://www.ncbi.nlm.nih.gov/pubmed/18047700
http://dx.doi.org/10.1186/gb-2007-8-s1-s8
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author Korzh, Vladimir
author_facet Korzh, Vladimir
author_sort Korzh, Vladimir
collection PubMed
description DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective.
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spelling pubmed-21068352007-12-05 Transposons as tools for enhancer trap screens in vertebrates Korzh, Vladimir Genome Biol Review DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective. BioMed Central 2007 2007-10-31 /pmc/articles/PMC2106835/ /pubmed/18047700 http://dx.doi.org/10.1186/gb-2007-8-s1-s8 Text en Copyright © 2007 BioMed Central Ltd
spellingShingle Review
Korzh, Vladimir
Transposons as tools for enhancer trap screens in vertebrates
title Transposons as tools for enhancer trap screens in vertebrates
title_full Transposons as tools for enhancer trap screens in vertebrates
title_fullStr Transposons as tools for enhancer trap screens in vertebrates
title_full_unstemmed Transposons as tools for enhancer trap screens in vertebrates
title_short Transposons as tools for enhancer trap screens in vertebrates
title_sort transposons as tools for enhancer trap screens in vertebrates
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106835/
https://www.ncbi.nlm.nih.gov/pubmed/18047700
http://dx.doi.org/10.1186/gb-2007-8-s1-s8
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