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Transposons as tools for enhancer trap screens in vertebrates
DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106835/ https://www.ncbi.nlm.nih.gov/pubmed/18047700 http://dx.doi.org/10.1186/gb-2007-8-s1-s8 |
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author | Korzh, Vladimir |
author_facet | Korzh, Vladimir |
author_sort | Korzh, Vladimir |
collection | PubMed |
description | DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective. |
format | Text |
id | pubmed-2106835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-21068352007-12-05 Transposons as tools for enhancer trap screens in vertebrates Korzh, Vladimir Genome Biol Review DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective. BioMed Central 2007 2007-10-31 /pmc/articles/PMC2106835/ /pubmed/18047700 http://dx.doi.org/10.1186/gb-2007-8-s1-s8 Text en Copyright © 2007 BioMed Central Ltd |
spellingShingle | Review Korzh, Vladimir Transposons as tools for enhancer trap screens in vertebrates |
title | Transposons as tools for enhancer trap screens in vertebrates |
title_full | Transposons as tools for enhancer trap screens in vertebrates |
title_fullStr | Transposons as tools for enhancer trap screens in vertebrates |
title_full_unstemmed | Transposons as tools for enhancer trap screens in vertebrates |
title_short | Transposons as tools for enhancer trap screens in vertebrates |
title_sort | transposons as tools for enhancer trap screens in vertebrates |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106835/ https://www.ncbi.nlm.nih.gov/pubmed/18047700 http://dx.doi.org/10.1186/gb-2007-8-s1-s8 |
work_keys_str_mv | AT korzhvladimir transposonsastoolsforenhancertrapscreensinvertebrates |