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Transposable elements in fish functional genomics: technical challenges and perspectives

The recent introduction of several transposable elements in zebrafish opens new frontiers for genetic manipulation in this important vertebrate model. This review discusses transposable elements as mutagenesis tools for fish functional genomics. We review various mutagenesis strategies that were pre...

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Detalles Bibliográficos
Autores principales: Parinov, Serguei, Emelyanov, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106837/
https://www.ncbi.nlm.nih.gov/pubmed/18047698
http://dx.doi.org/10.1186/gb-2007-8-s1-s6
Descripción
Sumario:The recent introduction of several transposable elements in zebrafish opens new frontiers for genetic manipulation in this important vertebrate model. This review discusses transposable elements as mutagenesis tools for fish functional genomics. We review various mutagenesis strategies that were previously applied in other genetic models, such as Drosophila, Arabidopsis, and mouse, that may be beneficial if applied in fish. We also discuss the forthcoming challenges of high-throughput functional genomics in fish.