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Retroviral enhancer detection insertions in zebrafish combined with comparative genomics reveal genomic regulatory blocks - a fundamental feature of vertebrate genomes
A large-scale enhancer detection screen was performed in the zebrafish using a retroviral vector carrying a basal promoter and a fluorescent protein reporter cassette. Analysis of insertional hotspots uncovered areas around developmental regulatory genes in which an insertion results in the same glo...
Autores principales: | Kikuta, Hiroshi, Fredman, David, Rinkwitz, Silke, Lenhard, Boris, Becker, Thomas S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106839/ https://www.ncbi.nlm.nih.gov/pubmed/18047696 http://dx.doi.org/10.1186/gb-2007-8-s1-s4 |
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