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Mutagenesis in rodents using the L1 retrotransposon

LINE1 (L1) retrotransposons are genetic elements that are present in all mammalian genomes. L1s are active in both humans and mice, and are capable of copying themselves and inserting the copy into a new genomic location. These de novo insertions occasionally result in disease. Endogenous L1 retrotr...

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Detalles Bibliográficos
Autores principales: Ostertag, Eric M, Madison, Blair B, Kano, Hiroki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106842/
https://www.ncbi.nlm.nih.gov/pubmed/18047693
http://dx.doi.org/10.1186/gb-2007-8-s1-s16

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