Cargando…

Transposons for cancer gene discovery: Sleeping Beauty and beyond

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.

Detalles Bibliográficos
Autores principales:	Collier, Lara S, Largaespada, David A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106843/ https://www.ncbi.nlm.nih.gov/pubmed/18047692 http://dx.doi.org/10.1186/gb-2007-8-s1-s15

Ejemplares similares

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon
por: Geurts, Aron M, et al.
Publicado: (2006)

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens
por: Temiz, Nuri A., et al.
Publicado: (2016)

Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis
por: Takeda, Haruna, et al.
Publicado: (2021)

Effective Gene Trapping Mediated by Sleeping Beauty Transposon
por: Song, Guili, et al.
Publicado: (2012)

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen
por: Ho, Yen-Yi, et al.
Publicado: (2016)

Germline mutagenesis mediated by Sleeping Beauty transposon system in mice
por: Takeda, Junji, et al.
Publicado: (2007)

Genetic Signature of Histiocytic Sarcoma Revealed by a Sleeping Beauty Transposon Genetic Screen in Mice
por: Been, Raha A., et al.
Publicado: (2014)

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes
por: Elso, Colleen M., et al.
Publicado: (2015)

Somatic Mutagenesis with a Sleeping Beauty Transposon System Leads to Solid Tumor Formation in Zebrafish
por: McGrail, Maura, et al.
Publicado: (2011)

Future perspectives of Sleeping Beauty transposon system in cancer research
por: Chen, Xiu, et al.
Publicado: (2019)

Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis
por: Yergeau, Donald A, et al.
Publicado: (2011)

Enhancer trapping in zebrafish using the Sleeping Beauty transposon
por: Balciunas, Darius, et al.
Publicado: (2004)

Restoration of dystrophin expression using the Sleeping Beauty transposon
por: Muses, Sofia, et al.
Publicado: (2012)

Sleeping Beauty transposon integrates into non-TA dinucleotides
por: Guo, Yabin, et al.
Publicado: (2018)

Sleeping Beauty Transposon-Mediated Asparaginase Gene Delivery by a Nanoparticle Platform
por: Chang, Jen-Hsuan, et al.
Publicado: (2019)

Compact Bidirectional Promoters for Dual-Gene Expression in a Sleeping Beauty Transposon
por: He, Kevin, et al.
Publicado: (2020)

Engineered Sleeping Beauty transposase redirects transposon integration away from genes
por: Miskey, Csaba, et al.
Publicado: (2022)

Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B cell acute lymphoblastic leukemia
por: Heltemes-Harris, Lynn M., et al.
Publicado: (2015)

High-performance gene expression and knockout tools using sleeping beauty transposon system
por: Hu, Kaishun, et al.
Publicado: (2018)

Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells
por: Wang, Yongming, et al.
Publicado: (2014)

Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells
por: Turchiano, Giandomenico, et al.
Publicado: (2014)

Development of a Mouse Model of Prostate Cancer Using the Sleeping Beauty Transposon and Electroporation
por: Choi, Hyun-Ji, et al.
Publicado: (2018)

Evolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty
por: Scheuermann, Barbara, et al.
Publicado: (2019)

Correction to: High-performance gene expression and knockout tools using sleeping beauty transposon system
por: Hu, Kaishun, et al.
Publicado: (2019)

Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers
por: Kolacsek, Orsolya, et al.
Publicado: (2011)

Correction: Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells
por: Wang, Yongming, et al.
Publicado: (2019)

Correction: Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells
por: Turchiano, Giandomenico, et al.
Publicado: (2020)

Engineered Sleeping Beauty Transposon as Efficient System to Optimize Chimp Adenoviral Production
por: Baldassarri, Samantha, et al.
Publicado: (2022)

Sleeping Beauty Transposon Insertions into Nucleolar DNA by an Engineered Transposase Localized in the Nucleolus
por: Kovač, Adrian, et al.
Publicado: (2023)

Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System
por: Belur, Lalitha R, et al.
Publicado: (2011)

Transposon Insertion Mutagenesis in Mice for Modeling Human Cancers: Critical Insights Gained and New Opportunities
por: Beckmann, Pauline J., et al.
Publicado: (2020)

Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development
por: Shimomura, Kana, et al.
Publicado: (2023)

Structure-based prediction of insertion-site preferences of transposons into chromosomes
por: Geurts, Aron M., et al.
Publicado: (2006)

Correction: Reliable transgene-independent method for determining sleeping beauty transposon copy numbers
por: Kolacsek, Orsolya, et al.
Publicado: (2013)

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice
por: Loeb, Keith R., et al.
Publicado: (2019)

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences
por: Zhou, Yiting, et al.
Publicado: (2021)

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors
por: Holstein, Marta, et al.
Publicado: (2018)

Universal allogeneic CAR T cells engineered with Sleeping Beauty transposons and CRISPR-CAS9 for cancer immunotherapy
por: Tipanee, Jaitip, et al.
Publicado: (2022)

Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells
por: Grabundzija, Ivana, et al.
Publicado: (2013)

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization
por: Hernandez, Maria, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_89vv9uai8gsudvdr9e1fr3vmcv