Insertional mutagenesis strategies in zebrafish

We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, includ...

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Detalles Bibliográficos
Autores principales: Sivasubbu, Sridhar, Balciunas, Darius, Amsterdam, Adam, Ekker, Stephen C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106850/
https://www.ncbi.nlm.nih.gov/pubmed/18047701
http://dx.doi.org/10.1186/gb-2007-8-s1-s9
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author Sivasubbu, Sridhar
Balciunas, Darius
Amsterdam, Adam
Ekker, Stephen C
author_facet Sivasubbu, Sridhar
Balciunas, Darius
Amsterdam, Adam
Ekker, Stephen C
author_sort Sivasubbu, Sridhar
collection PubMed
description We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.
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spelling pubmed-21068502007-12-05 Insertional mutagenesis strategies in zebrafish Sivasubbu, Sridhar Balciunas, Darius Amsterdam, Adam Ekker, Stephen C Genome Biol Review We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches. BioMed Central 2007 2007-10-31 /pmc/articles/PMC2106850/ /pubmed/18047701 http://dx.doi.org/10.1186/gb-2007-8-s1-s9 Text en Copyright © 2007 BioMed Central Ltd
spellingShingle Review
Sivasubbu, Sridhar
Balciunas, Darius
Amsterdam, Adam
Ekker, Stephen C
Insertional mutagenesis strategies in zebrafish
title Insertional mutagenesis strategies in zebrafish
title_full Insertional mutagenesis strategies in zebrafish
title_fullStr Insertional mutagenesis strategies in zebrafish
title_full_unstemmed Insertional mutagenesis strategies in zebrafish
title_short Insertional mutagenesis strategies in zebrafish
title_sort insertional mutagenesis strategies in zebrafish
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106850/
https://www.ncbi.nlm.nih.gov/pubmed/18047701
http://dx.doi.org/10.1186/gb-2007-8-s1-s9
work_keys_str_mv AT sivasubbusridhar insertionalmutagenesisstrategiesinzebrafish
AT balciunasdarius insertionalmutagenesisstrategiesinzebrafish
AT amsterdamadam insertionalmutagenesisstrategiesinzebrafish
AT ekkerstephenc insertionalmutagenesisstrategiesinzebrafish

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