ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule

Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical i...

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Detalles Bibliográficos
Autores principales: Greider, Marie H., Howell, S. L., Lacy, P. E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1969
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107726/
https://www.ncbi.nlm.nih.gov/pubmed/4887228
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author Greider, Marie H.
Howell, S. L.
Lacy, P. E.
author_facet Greider, Marie H.
Howell, S. L.
Lacy, P. E.
author_sort Greider, Marie H.
collection PubMed
description Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material.
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spelling pubmed-21077262008-05-01 ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule Greider, Marie H. Howell, S. L. Lacy, P. E. J Cell Biol Article Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material. The Rockefeller University Press 1969-04-01 /pmc/articles/PMC2107726/ /pubmed/4887228 Text en Copyright © 1969 by The Rockefeller University Press. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Greider, Marie H.
Howell, S. L.
Lacy, P. E.
ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title_full ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title_fullStr ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title_full_unstemmed ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title_short ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : II. Ultrastructure of the Beta Granule
title_sort isolation and properties of secretory granules from rat islets of langerhans : ii. ultrastructure of the beta granule
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107726/
https://www.ncbi.nlm.nih.gov/pubmed/4887228
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AT lacype isolationandpropertiesofsecretorygranulesfromratisletsoflangerhansiiultrastructureofthebetagranule

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