OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes

Unit cell dimensions of mitochondrial crystals were determined by optical diffraction analysis of electron micrographs of human liver biopsy specimens. Identical unit cells were found in pathologic material obtained from six patients with Wilson's disease, from one patient with sickle-cell hepa...

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Detalles Bibliográficos
Autores principales: Sternlieb, Irmin, Berger, Jacob E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1969
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107803/
https://www.ncbi.nlm.nih.gov/pubmed/5351401
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author Sternlieb, Irmin
Berger, Jacob E.
author_facet Sternlieb, Irmin
Berger, Jacob E.
author_sort Sternlieb, Irmin
collection PubMed
description Unit cell dimensions of mitochondrial crystals were determined by optical diffraction analysis of electron micrographs of human liver biopsy specimens. Identical unit cells were found in pathologic material obtained from six patients with Wilson's disease, from one patient with sickle-cell hepatitis, and from two normal subjects. These measurements led to the conclusion that the crystals observed in patients and in normal subjects were probably chemically identical. Furthermore, the relatively large size of the unit cell limits the choices for its constituents to phospholipid micelles or to relatively large protein molecules.
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spelling pubmed-21078032008-05-01 OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes Sternlieb, Irmin Berger, Jacob E. J Cell Biol Article Unit cell dimensions of mitochondrial crystals were determined by optical diffraction analysis of electron micrographs of human liver biopsy specimens. Identical unit cells were found in pathologic material obtained from six patients with Wilson's disease, from one patient with sickle-cell hepatitis, and from two normal subjects. These measurements led to the conclusion that the crystals observed in patients and in normal subjects were probably chemically identical. Furthermore, the relatively large size of the unit cell limits the choices for its constituents to phospholipid micelles or to relatively large protein molecules. The Rockefeller University Press 1969-12-01 /pmc/articles/PMC2107803/ /pubmed/5351401 Text en Copyright © 1969 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sternlieb, Irmin
Berger, Jacob E.
OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title_full OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title_fullStr OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title_full_unstemmed OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title_short OPTICAL DIFFRACTION STUDIES OF CRYSTALLINE STRUCTURES IN ELECTRON MICROGRAPHS : II. Crystalline Inclusions in Mitochondria of Human Hepatocytes
title_sort optical diffraction studies of crystalline structures in electron micrographs : ii. crystalline inclusions in mitochondria of human hepatocytes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107803/
https://www.ncbi.nlm.nih.gov/pubmed/5351401
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AT bergerjacobe opticaldiffractionstudiesofcrystallinestructuresinelectronmicrographsiicrystallineinclusionsinmitochondriaofhumanhepatocytes

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