Cargando…

A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE

HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G(1), S, and G(2) portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments. The results indicated that some of the HnRNA molecules were equivalent at all times in the cell cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Pagoulatos, Gerassimos N., Darnell, James E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107977/
https://www.ncbi.nlm.nih.gov/pubmed/5415232
_version_ 1782138922656071680
author Pagoulatos, Gerassimos N.
Darnell, James E.
author_facet Pagoulatos, Gerassimos N.
Darnell, James E.
author_sort Pagoulatos, Gerassimos N.
collection PubMed
description HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G(1), S, and G(2) portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments. The results indicated that some of the HnRNA molecules were equivalent at all times in the cell cycle, but limitations in the sensitivity of the hydridization reactions, as well as in the spectrum of hybridizing molecules, restrict the conclusions that can be drawn from these comparisons.
format Text
id pubmed-2107977
institution National Center for Biotechnology Information
language English
publishDate 1970
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21079772008-05-01 A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE Pagoulatos, Gerassimos N. Darnell, James E. J Cell Biol Article HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G(1), S, and G(2) portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments. The results indicated that some of the HnRNA molecules were equivalent at all times in the cell cycle, but limitations in the sensitivity of the hydridization reactions, as well as in the spectrum of hybridizing molecules, restrict the conclusions that can be drawn from these comparisons. The Rockefeller University Press 1970-03-01 /pmc/articles/PMC2107977/ /pubmed/5415232 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Pagoulatos, Gerassimos N.
Darnell, James E.
A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title_full A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title_fullStr A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title_full_unstemmed A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title_short A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
title_sort comparison of the heterogeneous nuclear rna of hela cells in different periods of the cell growth cycle
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107977/
https://www.ncbi.nlm.nih.gov/pubmed/5415232
work_keys_str_mv AT pagoulatosgerassimosn acomparisonoftheheterogeneousnuclearrnaofhelacellsindifferentperiodsofthecellgrowthcycle
AT darnelljamese acomparisonoftheheterogeneousnuclearrnaofhelacellsindifferentperiodsofthecellgrowthcycle
AT pagoulatosgerassimosn comparisonoftheheterogeneousnuclearrnaofhelacellsindifferentperiodsofthecellgrowthcycle
AT darnelljamese comparisonoftheheterogeneousnuclearrnaofhelacellsindifferentperiodsofthecellgrowthcycle