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THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES
The spatial reconstruction of the XY pair of chromosomes from human spermatocytes has been made by the study of serial sections 1000 A in thickness. The sex pair during zygotene-pachytene forms a condensed mass of chromatin that has two filamentous, electron-opaque cores: the long and the short core...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1970
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107993/ https://www.ncbi.nlm.nih.gov/pubmed/5458999 |
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author | Solari, A. J. Tres, Laura L. |
author_facet | Solari, A. J. Tres, Laura L. |
author_sort | Solari, A. J. |
collection | PubMed |
description | The spatial reconstruction of the XY pair of chromosomes from human spermatocytes has been made by the study of serial sections 1000 A in thickness. The sex pair during zygotene-pachytene forms a condensed mass of chromatin that has two filamentous, electron-opaque cores: the long and the short core. During early pachytene both cores have a common ending region, about 0.4–0.8 µ long. This common end is a synaptonemal complex, and each of the cores forms a lateral element of that complex. The cores become more convoluted during middle pachytene forming "ringlike bodies." Nucleoli from spermatocytes have three distinct regions: (a) granular; (b) dense fibrillar; and (c) clear intermediate. Occasional association of the XY pair and the heteropycnotic "basal knobs" results in apparent association of nucleoli and the sex pair in a minority of cells. The evidence presented is interpreted as a strong support of the hypothesis of homologous regions in the human XY pair. |
format | Text |
id | pubmed-2107993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1970 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21079932008-05-01 THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES Solari, A. J. Tres, Laura L. J Cell Biol Article The spatial reconstruction of the XY pair of chromosomes from human spermatocytes has been made by the study of serial sections 1000 A in thickness. The sex pair during zygotene-pachytene forms a condensed mass of chromatin that has two filamentous, electron-opaque cores: the long and the short core. During early pachytene both cores have a common ending region, about 0.4–0.8 µ long. This common end is a synaptonemal complex, and each of the cores forms a lateral element of that complex. The cores become more convoluted during middle pachytene forming "ringlike bodies." Nucleoli from spermatocytes have three distinct regions: (a) granular; (b) dense fibrillar; and (c) clear intermediate. Occasional association of the XY pair and the heteropycnotic "basal knobs" results in apparent association of nucleoli and the sex pair in a minority of cells. The evidence presented is interpreted as a strong support of the hypothesis of homologous regions in the human XY pair. The Rockefeller University Press 1970-04-01 /pmc/articles/PMC2107993/ /pubmed/5458999 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Solari, A. J. Tres, Laura L. THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title | THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title_full | THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title_fullStr | THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title_full_unstemmed | THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title_short | THE THREE-DIMENSIONAL RECONSTRUCTION OF THE XY CHROMOSOMAL PAIR IN HUMAN SPERMATOCYTES |
title_sort | three-dimensional reconstruction of the xy chromosomal pair in human spermatocytes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2107993/ https://www.ncbi.nlm.nih.gov/pubmed/5458999 |
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