ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL

Cortisol can prematurely induce glutamine synthetase activity in the chick embryo retina. Under appropriate conditions, this effect can be enhanced by addition of low levels of actinomycin D; this enhancement is reversibly inhibited by cycloheximide. The magnitude of the effect is a function of time...

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Detalles Bibliográficos
Autor principal: Beif-Lehrer, Liane
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1971
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108240/
https://www.ncbi.nlm.nih.gov/pubmed/4398761
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author Beif-Lehrer, Liane
author_facet Beif-Lehrer, Liane
author_sort Beif-Lehrer, Liane
collection PubMed
description Cortisol can prematurely induce glutamine synthetase activity in the chick embryo retina. Under appropriate conditions, this effect can be enhanced by addition of low levels of actinomycin D; this enhancement is reversibly inhibited by cycloheximide. The magnitude of the effect is a function of time of exposure to hormone as well as antibiotic and is also a function of the age of the embryo; within the limits of the present study it did not appear to be a function of actinomycin-D concentration. The data are discussed in terms of current ideas of possible control mechanisms in animal cells.
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spelling pubmed-21082402008-05-01 ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL Beif-Lehrer, Liane J Cell Biol Article Cortisol can prematurely induce glutamine synthetase activity in the chick embryo retina. Under appropriate conditions, this effect can be enhanced by addition of low levels of actinomycin D; this enhancement is reversibly inhibited by cycloheximide. The magnitude of the effect is a function of time of exposure to hormone as well as antibiotic and is also a function of the age of the embryo; within the limits of the present study it did not appear to be a function of actinomycin-D concentration. The data are discussed in terms of current ideas of possible control mechanisms in animal cells. The Rockefeller University Press 1971-10-01 /pmc/articles/PMC2108240/ /pubmed/4398761 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Beif-Lehrer, Liane
ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title_full ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title_fullStr ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title_full_unstemmed ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title_short ACTINOMYCIN-D ENHANCEMENT OF GLUTAMINE SYNTHETASE ACTIVITY IN CHICK EMBRYO RETINAS CULTURED IN THE PRESENCE OF CORTISOL
title_sort actinomycin-d enhancement of glutamine synthetase activity in chick embryo retinas cultured in the presence of cortisol
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108240/
https://www.ncbi.nlm.nih.gov/pubmed/4398761
work_keys_str_mv AT beiflehrerliane actinomycindenhancementofglutaminesynthetaseactivityinchickembryoretinasculturedinthepresenceofcortisol

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