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THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS
Attempts were made to test the motile functions of bundles of microfilaments found in baby hamster kidney (BHK-21) cells, by using cytochalasin B (CB). It was found that individual cells respond differently to the drug. These differential effects are quite obvious in both light and electron microsco...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1972
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108645/ https://www.ncbi.nlm.nih.gov/pubmed/5061947 |
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author | Goldman, Robert D. |
author_facet | Goldman, Robert D. |
author_sort | Goldman, Robert D. |
collection | PubMed |
description | Attempts were made to test the motile functions of bundles of microfilaments found in baby hamster kidney (BHK-21) cells, by using cytochalasin B (CB). It was found that individual cells respond differently to the drug. These differential effects are quite obvious in both light and electron microscope preparations. Some cells contain normal bundles of microfilaments even after 24 hr in CB, and other cells form muscle-like configurations which also contain arrays of microfilaments. These varied effects suggest the existence of several types of microfilaments in BHK-21 cells, and make the interpretation of the motile role of microfilaments difficult to evaluate at the present time. |
format | Text |
id | pubmed-2108645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1972 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21086452008-05-01 THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS Goldman, Robert D. J Cell Biol Article Attempts were made to test the motile functions of bundles of microfilaments found in baby hamster kidney (BHK-21) cells, by using cytochalasin B (CB). It was found that individual cells respond differently to the drug. These differential effects are quite obvious in both light and electron microscope preparations. Some cells contain normal bundles of microfilaments even after 24 hr in CB, and other cells form muscle-like configurations which also contain arrays of microfilaments. These varied effects suggest the existence of several types of microfilaments in BHK-21 cells, and make the interpretation of the motile role of microfilaments difficult to evaluate at the present time. The Rockefeller University Press 1972-02-01 /pmc/articles/PMC2108645/ /pubmed/5061947 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Goldman, Robert D. THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title | THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title_full | THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title_fullStr | THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title_full_unstemmed | THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title_short | THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS |
title_sort | effects of cytochalasin b on the microfilaments of baby hamster kidney (bhk-21) cells |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108645/ https://www.ncbi.nlm.nih.gov/pubmed/5061947 |
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