SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis

From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 10(8) to 6.99 x 10(8) molecules of sur...

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Detalles Bibliográficos
Autores principales: Rosenberg, Steven A., Einstein, Albert B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108726/
https://www.ncbi.nlm.nih.gov/pubmed/4502785
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author Rosenberg, Steven A.
Einstein, Albert B.
author_facet Rosenberg, Steven A.
Einstein, Albert B.
author_sort Rosenberg, Steven A.
collection PubMed
description From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 10(8) to 6.99 x 10(8) molecules of surface sialic acid per cell. In synchronized cultures synthesis of surface sialic acid occurs only during a limited time in the late G(2) phase of the cell cycle. The amount and density of surface sialic acid vary considerably throughout the cell cycle.
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spelling pubmed-21087262008-05-01 SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis Rosenberg, Steven A. Einstein, Albert B. J Cell Biol Article From 61 to 92% of the total sialic acid of a variety of human lymphoid cell lines maintained in tissue culture is present on the cell surface as measured by its susceptibility to cleavage by Clostridium perfringens neuraminidase. These cells contain from 1.22 x 10(8) to 6.99 x 10(8) molecules of surface sialic acid per cell. In synchronized cultures synthesis of surface sialic acid occurs only during a limited time in the late G(2) phase of the cell cycle. The amount and density of surface sialic acid vary considerably throughout the cell cycle. The Rockefeller University Press 1972-05-01 /pmc/articles/PMC2108726/ /pubmed/4502785 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Rosenberg, Steven A.
Einstein, Albert B.
SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_full SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_fullStr SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_full_unstemmed SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_short SIALIC ACIDS ON THE PLASMA MEMBRANE OF CULTURED HUMAN LYMPHOID CELLS : Chemical Aspects and Biosynthesis
title_sort sialic acids on the plasma membrane of cultured human lymphoid cells : chemical aspects and biosynthesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108726/
https://www.ncbi.nlm.nih.gov/pubmed/4502785
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