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ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT
Nuclear transplantations and electron microscope autoradiographv (EMRA) were utilized in order to localize and characterize small nuclear RNA's (snRNA) in ameba nuclei. A class of nonmigrating low molecular weight nuclear RNA's is associated with the structureless region of the nucleoplasm...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1973
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108845/ https://www.ncbi.nlm.nih.gov/pubmed/4629880 |
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author | Wise, Gary E. Goldstein, Lester |
author_facet | Wise, Gary E. Goldstein, Lester |
author_sort | Wise, Gary E. |
collection | PubMed |
description | Nuclear transplantations and electron microscope autoradiographv (EMRA) were utilized in order to localize and characterize small nuclear RNA's (snRNA) in ameba nuclei. A class of nonmigrating low molecular weight nuclear RNA's is associated with the structureless region of the nucleoplasm but not with the nucleoli, nuclear helices, or chromatin Thus, the role of these RNA's in genetic regulation is questionable A class of migrating RNA's (presumed, but not directly shown, to be low molecular weight) that shuttles between nucleus and cytoplasm is also not associated with nucleoli or helices but some radioactivity is associated with the chromatin It may be, therefore, that the shuttling RNA's are in some way involved in genetic transcription or replication. |
format | Text |
id | pubmed-2108845 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1973 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21088452008-05-01 ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT Wise, Gary E. Goldstein, Lester J Cell Biol Article Nuclear transplantations and electron microscope autoradiographv (EMRA) were utilized in order to localize and characterize small nuclear RNA's (snRNA) in ameba nuclei. A class of nonmigrating low molecular weight nuclear RNA's is associated with the structureless region of the nucleoplasm but not with the nucleoli, nuclear helices, or chromatin Thus, the role of these RNA's in genetic regulation is questionable A class of migrating RNA's (presumed, but not directly shown, to be low molecular weight) that shuttles between nucleus and cytoplasm is also not associated with nucleoli or helices but some radioactivity is associated with the chromatin It may be, therefore, that the shuttling RNA's are in some way involved in genetic transcription or replication. The Rockefeller University Press 1973-01-01 /pmc/articles/PMC2108845/ /pubmed/4629880 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Wise, Gary E. Goldstein, Lester ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title | ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title_full | ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title_fullStr | ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title_full_unstemmed | ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title_short | ELECTRON MICROSCOPE LOCALIZATION OF NUCLEAR RNA'S THAT SHUTTLE BETWEEN CYTOPLASM AND NUCLEUS AND NUCLEAR RNA'S THAT DO NOT |
title_sort | electron microscope localization of nuclear rna's that shuttle between cytoplasm and nucleus and nuclear rna's that do not |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108845/ https://www.ncbi.nlm.nih.gov/pubmed/4629880 |
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