A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE

A morphometric study of the nexus of rat cardiac muscle was carried out. The nexus surface of one intercalated disk of one 15 µm thick fiber is found to range between 47 µm(2) and 94 µm(2), the latter value taking into account the maximal underestimation caused by tangential sectioning. Dividing the...

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Detalles Bibliográficos
Autor principal: Matter, Alex
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108931/
https://www.ncbi.nlm.nih.gov/pubmed/4687914
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author Matter, Alex
author_facet Matter, Alex
author_sort Matter, Alex
collection PubMed
description A morphometric study of the nexus of rat cardiac muscle was carried out. The nexus surface of one intercalated disk of one 15 µm thick fiber is found to range between 47 µm(2) and 94 µm(2), the latter value taking into account the maximal underestimation caused by tangential sectioning. Dividing the lower, minimal value by the surface of the observed subunits (90 Å periodicity), one obtains for one intercalated disk 6.7 x 10(5) subunits, each of them assumed to be permeated by a central pore. These pores are thought to be equivalent to intercellular channels in a recently proposed model. Taking our morphometric and recently reported physiological values, this model is examined for its consistency with a low resistance pathway between cardiac muscle cells.
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spelling pubmed-21089312008-05-01 A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE Matter, Alex J Cell Biol Article A morphometric study of the nexus of rat cardiac muscle was carried out. The nexus surface of one intercalated disk of one 15 µm thick fiber is found to range between 47 µm(2) and 94 µm(2), the latter value taking into account the maximal underestimation caused by tangential sectioning. Dividing the lower, minimal value by the surface of the observed subunits (90 Å periodicity), one obtains for one intercalated disk 6.7 x 10(5) subunits, each of them assumed to be permeated by a central pore. These pores are thought to be equivalent to intercellular channels in a recently proposed model. Taking our morphometric and recently reported physiological values, this model is examined for its consistency with a low resistance pathway between cardiac muscle cells. The Rockefeller University Press 1973-03-01 /pmc/articles/PMC2108931/ /pubmed/4687914 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Matter, Alex
A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title_full A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title_fullStr A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title_full_unstemmed A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title_short A MORPHOMETRIC STUDY ON THE NEXUS OF RAT CARDIAC MUSCLE
title_sort morphometric study on the nexus of rat cardiac muscle
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2108931/
https://www.ncbi.nlm.nih.gov/pubmed/4687914
work_keys_str_mv AT matteralex amorphometricstudyonthenexusofratcardiacmuscle
AT matteralex morphometricstudyonthenexusofratcardiacmuscle

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