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Changes in tight junctions of thyroid epithelium with changes in thyroid activity
The morphology of the tight junction of rat thyroid epithelium was examined in freeze-fractured material fixed in glutaraldehyde and briefly glycerinated. In normal thyroids the overall appearance of this junctional specialization resembled that of other cell types in many respects. Short-term chang...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1975
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109449/ https://www.ncbi.nlm.nih.gov/pubmed/1158975 |
| _version_ | 1782139298620899328 |
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| collection | PubMed |
| description | The morphology of the tight junction of rat thyroid epithelium was examined in freeze-fractured material fixed in glutaraldehyde and briefly glycerinated. In normal thyroids the overall appearance of this junctional specialization resembled that of other cell types in many respects. Short-term changes in thyroid activity and hypophysectomy for 3 wk did not obviously affect the appearance of tight junctions. Feeding of the goitrogen, thiouracil, which stimulates secretion of thyroid-stimulating hormone, resulted in the appearance of some very narrow and some very wide, tight junctions or sometimes junctions with both wide and narrow regions within the same cell. |
| format | Text |
| id | pubmed-2109449 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1975 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21094492008-05-01 Changes in tight junctions of thyroid epithelium with changes in thyroid activity J Cell Biol Articles The morphology of the tight junction of rat thyroid epithelium was examined in freeze-fractured material fixed in glutaraldehyde and briefly glycerinated. In normal thyroids the overall appearance of this junctional specialization resembled that of other cell types in many respects. Short-term changes in thyroid activity and hypophysectomy for 3 wk did not obviously affect the appearance of tight junctions. Feeding of the goitrogen, thiouracil, which stimulates secretion of thyroid-stimulating hormone, resulted in the appearance of some very narrow and some very wide, tight junctions or sometimes junctions with both wide and narrow regions within the same cell. The Rockefeller University Press 1975-09-01 /pmc/articles/PMC2109449/ /pubmed/1158975 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Articles Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title | Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title_full | Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title_fullStr | Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title_full_unstemmed | Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title_short | Changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| title_sort | changes in tight junctions of thyroid epithelium with changes in thyroid activity |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109449/ https://www.ncbi.nlm.nih.gov/pubmed/1158975 |