Effects of serotonin, carbamylcholine, and ascorbic acid on leukocyte cyclic GMP and chemotaxis

Serotonin, ascorbic acid, and carbamylcholine enhanced the chemotactic responsiveness of human monocytes to endotoxin-treated serum. These agents caused significant accumulation of cyclic GMP in monocytes. PMN leukocyte chemotaxis was also enhanced by these agents although significant increases in c...

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Detalles Bibliográficos
Autores principales: Sandler, J. A., Gallin, J. I., Vaughan, M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Journal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109603/
https://www.ncbi.nlm.nih.gov/pubmed/172514
Descripción
Sumario:Serotonin, ascorbic acid, and carbamylcholine enhanced the chemotactic responsiveness of human monocytes to endotoxin-treated serum. These agents caused significant accumulation of cyclic GMP in monocytes. PMN leukocyte chemotaxis was also enhanced by these agents although significant increases in cyclic GMP were not demonstrated.

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