Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography

Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in var...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109627/
https://www.ncbi.nlm.nih.gov/pubmed/1245552
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description Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons.
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spelling pubmed-21096272008-05-01 Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography J Cell Biol Articles Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons. The Rockefeller University Press 1976-02-01 /pmc/articles/PMC2109627/ /pubmed/1245552 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title_full Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title_fullStr Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title_full_unstemmed Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title_short Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography
title_sort glycine-specific synapses in rat spinal cord. identification by electron microscope autoradiography
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109627/
https://www.ncbi.nlm.nih.gov/pubmed/1245552

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