Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles

Aged cells have significantly fewer food vacuoles and ingest fewer bacteria than young cells. Loss of food vacuoles was explained by a decreasing difference in the food vacuole formation and excretion rates; the formation rate declined more rapidly than the excretion rate, approaching equivalence at...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109760/
https://www.ncbi.nlm.nih.gov/pubmed/993263
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collection PubMed
description Aged cells have significantly fewer food vacuoles and ingest fewer bacteria than young cells. Loss of food vacuoles was explained by a decreasing difference in the food vacuole formation and excretion rates; the formation rate declined more rapidly than the excretion rate, approaching equivalence at 160 fissions, when the proportion of cells with no food vacuoles, in the presence of excess food, abruptly increased. A model for cellular aging is presented in which control of organelle numbers and cyclical interactions between the nucleus and cytoplasm may be of critical importance.
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spelling pubmed-21097602008-05-01 Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles J Cell Biol Articles Aged cells have significantly fewer food vacuoles and ingest fewer bacteria than young cells. Loss of food vacuoles was explained by a decreasing difference in the food vacuole formation and excretion rates; the formation rate declined more rapidly than the excretion rate, approaching equivalence at 160 fissions, when the proportion of cells with no food vacuoles, in the presence of excess food, abruptly increased. A model for cellular aging is presented in which control of organelle numbers and cyclical interactions between the nucleus and cytoplasm may be of critical importance. The Rockefeller University Press 1976-11-01 /pmc/articles/PMC2109760/ /pubmed/993263 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title_full Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title_fullStr Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title_full_unstemmed Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title_short Loss of endocytic capacity in aging Paramecium. The importance of cytoplasmic organelles
title_sort loss of endocytic capacity in aging paramecium. the importance of cytoplasmic organelles
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109760/
https://www.ncbi.nlm.nih.gov/pubmed/993263

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