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Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture

In contrast to total cell irradiation, local UV-microbeam irradiation can stimulate a significant diminution in the irradiated mature nucleoli in interphase mammalian cells in culture. This diminution is accompanied by the concomitant expansion of the unirradiated nucleoli within the same nucleus, a...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109795/
https://www.ncbi.nlm.nih.gov/pubmed/993275
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description In contrast to total cell irradiation, local UV-microbeam irradiation can stimulate a significant diminution in the irradiated mature nucleoli in interphase mammalian cells in culture. This diminution is accompanied by the concomitant expansion of the unirradiated nucleoli within the same nucleus, and the total nucleolar volume per nucleus does not change appreciably. It is suggested that these nucleolar volume changes are the result of the dispersion, migration, and redistribution of the nucleolar material between competitive nucleolar organizer regions of the interphase nucleus.
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spelling pubmed-21097952008-05-01 Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture J Cell Biol Articles In contrast to total cell irradiation, local UV-microbeam irradiation can stimulate a significant diminution in the irradiated mature nucleoli in interphase mammalian cells in culture. This diminution is accompanied by the concomitant expansion of the unirradiated nucleoli within the same nucleus, and the total nucleolar volume per nucleus does not change appreciably. It is suggested that these nucleolar volume changes are the result of the dispersion, migration, and redistribution of the nucleolar material between competitive nucleolar organizer regions of the interphase nucleus. The Rockefeller University Press 1976-12-01 /pmc/articles/PMC2109795/ /pubmed/993275 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title_full Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title_fullStr Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title_full_unstemmed Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title_short Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
title_sort nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109795/
https://www.ncbi.nlm.nih.gov/pubmed/993275