Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus

SV40 particles can apparently enter the nucleus intact. However, they do not leave the nucleus despite the high concentration present during the productive phase. We found structural evidence that SV40 virus is prevented from approaching the most likely site of exit, the nuclear pore complex. From t...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109846/
https://www.ncbi.nlm.nih.gov/pubmed/182701
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collection PubMed
description SV40 particles can apparently enter the nucleus intact. However, they do not leave the nucleus despite the high concentration present during the productive phase. We found structural evidence that SV40 virus is prevented from approaching the most likely site of exit, the nuclear pore complex. From these images, it is concluded that the fibrils attached to the nuclear pore complex prevent egress of SV40 particles from the infected nucleus.
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spelling pubmed-21098462008-05-01 Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus J Cell Biol Articles SV40 particles can apparently enter the nucleus intact. However, they do not leave the nucleus despite the high concentration present during the productive phase. We found structural evidence that SV40 virus is prevented from approaching the most likely site of exit, the nuclear pore complex. From these images, it is concluded that the fibrils attached to the nuclear pore complex prevent egress of SV40 particles from the infected nucleus. The Rockefeller University Press 1976-09-01 /pmc/articles/PMC2109846/ /pubmed/182701 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title_full Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title_fullStr Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title_full_unstemmed Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title_short Fibrils attached to the nuclear pore prevent egress of SV40 particles from the infected nucleus
title_sort fibrils attached to the nuclear pore prevent egress of sv40 particles from the infected nucleus
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109846/
https://www.ncbi.nlm.nih.gov/pubmed/182701

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