Actin filaments in sensory hairs of inner ear receptor cells

Receptor cells in the ear are excited through the bending of sensory hairs which project in a bundle from their surface. The individual stereocilia of a bundle contain filaments about 5 nm in diameter. The identity of these filaments has been investigated in the crista ampullaris of the frog and gui...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109950/
https://www.ncbi.nlm.nih.gov/pubmed/318131
_version_ 1782139445068169216
collection PubMed
description Receptor cells in the ear are excited through the bending of sensory hairs which project in a bundle from their surface. The individual stereocilia of a bundle contain filaments about 5 nm in diameter. The identity of these filaments has been investigated in the crista ampullaris of the frog and guinea pig by a technique of decoration with subfragment-1 of myosin (S-1). After demembranation with Triton X-100 and incubation with S-1, "arrowhead" formation was observed along the filaments of the stereocilia and their rootlets and also along filaments in the cuticular plate inside the receptor cell. The distance between attached S-1 was 35 nm and arrowheads pointed in towards the cell soma. It is concluded that the filaments of stereocilia are composed of actin.
format Text
id pubmed-2109950
institution National Center for Biotechnology Information
language English
publishDate 1977
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21099502008-05-01 Actin filaments in sensory hairs of inner ear receptor cells J Cell Biol Articles Receptor cells in the ear are excited through the bending of sensory hairs which project in a bundle from their surface. The individual stereocilia of a bundle contain filaments about 5 nm in diameter. The identity of these filaments has been investigated in the crista ampullaris of the frog and guinea pig by a technique of decoration with subfragment-1 of myosin (S-1). After demembranation with Triton X-100 and incubation with S-1, "arrowhead" formation was observed along the filaments of the stereocilia and their rootlets and also along filaments in the cuticular plate inside the receptor cell. The distance between attached S-1 was 35 nm and arrowheads pointed in towards the cell soma. It is concluded that the filaments of stereocilia are composed of actin. The Rockefeller University Press 1977-11-01 /pmc/articles/PMC2109950/ /pubmed/318131 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Actin filaments in sensory hairs of inner ear receptor cells
title Actin filaments in sensory hairs of inner ear receptor cells
title_full Actin filaments in sensory hairs of inner ear receptor cells
title_fullStr Actin filaments in sensory hairs of inner ear receptor cells
title_full_unstemmed Actin filaments in sensory hairs of inner ear receptor cells
title_short Actin filaments in sensory hairs of inner ear receptor cells
title_sort actin filaments in sensory hairs of inner ear receptor cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109950/
https://www.ncbi.nlm.nih.gov/pubmed/318131

Ejemplares similares